The Signal Peptide of Staphylococcus aureus Panton Valentine Leukocidin LukS Component Mediates Increased Adhesion to Heparan Sulfates
نویسندگان
چکیده
منابع مشابه
The Signal Peptide of Staphylococcus aureus Panton Valentine Leukocidin LukS Component Mediates Increased Adhesion to Heparan Sulfates
Staphylococcus aureus necrotizing pneumonia is a severe disease caused by S. aureus strains carrying the Panton Valentine leukocidin (PVL) genes (lukS-PV & lukF-PV) encoded on various bacteriophages (such as phiSLT). Clinical PVL+ strains isolated from necrotizing pneumonia display an increased attachment to matrix molecules (type I and IV collagens and laminin), a phenotype that could play a r...
متن کاملPanton-Valentine Leukocidin Genes in Staphylococcus aureus
To the Editor: The pathogenicity of Staphylococcus aureus depends on various bacterial surface components and extracellular proteins. However, the precise role of single virulence determinants in relation to infection is hard to establish. The frequent recovery of staphylococcal isolates that produce leukocidal toxins from patients with deep skin and soft tissue infections, particularly furuncu...
متن کاملPanton-Valentine Leukocidin–producing Staphylococcus aureus
To the Editor: Panton-Valentine leukocidin (PVL) is a cytotoxin produced by Staphylococcus aureus that causes leukocyte destruction and tissue necrosis (1). Although produced by <5% of S. aureus strains, the toxin is detected in large percentages of isolates that cause necrotic skin lesions and severe necrotizing pneumonia (2). Although commonly associated with community-acquired methicillin-re...
متن کاملPanton-Valentine Leukocidin–positive Staphylococcus aureus, Singapore
Trichinella papuae and Trichinella zimbab-wensis induce infection in experimentally infected varans, caimans, pythons and turtles. Trichinellosis: recommendations on methods for the control of Trichinella in domestic and wild animals intended for human consumption. La Rosa G. PCR-derived methods for the identification of Trichinella parasites from animal and human samples. The identification an...
متن کاملDetection of Novel Mutation in LukS Panton-Valentine Leukocidin Gene in Twelve Isolates of Staphylococcus aureus from Sudanese Patients
Staphylococcus aureus carrying PVL gene remain major health problem associated with highly virulent infections. Characterization of such gene is important to know the impact and the functional significance of nucleotide variations. PCR and standard sequencing were performed for twelve Sudanese strains from different sources. Protein structures prediction, modeling and physiochemical analysis we...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: PLoS ONE
سال: 2009
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0005042